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Good Laboratory Practices (GLP)
:: Laboratory Hazards

Laboratory Hazards

  • Contact with chemicals may cause external or internal injuries. External injuries are caused by skin exposure to caustic/corrosive chemicals (acid/base/reactive salts).
  • Prevent as far as possible inadvertent spills and splashes and equipment corrosion.
  • Internal injuries may result from toxic or corrosive effects of chemicals accidently ingested and absorbed by body.
  • Inorganic acids and bases have health and safety limits. Exposure to fumes can irritate or damage eye, skin and create respiratory problems.
  • Hot acids quickly react with the skin. Store acids and bases separately, in well-ventilated areas and away from volatile organic and oxidisable substances.
  • Slowly add strong acids and bases to water to avoid spattering. If there is an accidental skin contact, thoroughly flush the contaminated area with water and seek medical attention.
  • Perchloric acid reacts violently or explosively on contact with organic materials.
  • Don’t use perchloric acid together with organic reagents, particularly volatile solvents in one fume hood.
  • NaOH and certain other chemicals produce considerable heat on dissolution, which may cause burns.
  • Some metals (arsenic, nickel, mercury) are highly toxic and may also be carcinogenic. Avoid inhalation, ingestion and skin contact.
  • Nearly all organic solvents are hazardous. Some are probably carcinogenic and should be treated with extra caution.
  • Avoid mouth pipetting. Use of vacupads or auto pipettes is advisable.
  • Beware of physical hazards from electrical items and gas cylinders.
  • Never use glassware for HF (Hydrofluoric acid) treatment.
  • Always remember, HOT glassware looks exactly like COLD glassware, be careful while handling.


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